2 a.m. is a biological stress test no one talks about

What happens to your body and clinical judgment when you're managing a code blue at the exact hour your biology demands deep sleep? Chinyelu E. Oraedu is an academic hospitalist and nocturnist with 17 years of post-residency experience who has dedicated her career to understanding the science and human reality of night shift medicine. In this episode, based on her KevinMD article "How night shift medicine exposes the reality of physician stress," she breaks down why the 2 to 3 a.m. window is the most dangerous period for both patients and providers, when melatonin peaks, alertness bottoms out, and emergencies keep coming. You will learn practical strategies for surviving and thriving on night shift, from the right timing for caffeine intake to using light therapy at your workstation to suppress melatonin secretion. Oraedu explains why sleep is the single most important factor for night shift workers and why she tells every resident to protect it above exercise, meals, and everything else. She also shares surprising early data from her own research showing that night shift workers who build intentional structure around their schedule report high satisfaction. Whether you are an incoming intern about to start your first night float rotation or a seasoned nocturnist still battling fragmented sleep, this conversation offers a practical framework for reducing the hidden health risks of working against your circadian rhythm.

Tune into our episode "2026 Cholesterol Guidelines: LDL goals, lipoprotein(a), and coronary calcium scoring," brought to you by Novartis Pharmaceuticals Corporation.

For the first time in eight years, LDL cholesterol goals have changed, and preventive cardiologist Seth Baum says the new guidelines are a long-overdue course correction. He breaks down the new LDL targets for your highest-risk patients, why the LDL hypothesis should be retired in favor of the LDL fact, why lipoprotein(a) screening finally belongs in every patient's workup, what a coronary calcium score over 300 really means for how aggressively you treat, and how to talk to statin-skeptical patients without losing their trust. Listen now at KevinMD.com/cholesterol.

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