Why acne, chin hair, and irregular cycles are more than an ovary problem
A condition named for the ovaries turns out to run through the muscle, the liver, and the pancreas. Insulin is the signal connecting them, and different organs hear it differently. Oluyemisi Famuyiwa, reproductive endocrinologist and founder of the Montgomery Fertility Center, returns to walk through it. This episode is based on her article "How insulin drives polyendocrine metabolic ovarian syndrome," published on KevinMD. You will hear why the pancreas makes more insulin when muscle stops responding, and why the ovary and the liver are still listening when it does. You will hear what that does to androgen levels, and why acne, chin hair, and stubborn weight show up before irregular cycles. You will hear why body weight is a poor guide to who has PCOS, since lean patients carry the same elevated androgens and irregular cycles. And you will hear which tests she orders and why she works this across internal medicine and endocrinology. Press play for the reframe she leaves clinicians with: this is more than the ovary and more than insulin.
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